Monoclonal Antibodies – Section 1

16. The antigen-specific lymphocytes can be immortalized by which of the following method?

A. Transfection with tumor-derived DNA
B. Hybridization with a suitable lymphoid tumor cell
C. Transformation following infection by Epstein-Barr virus (EB V)
D. All of the above

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17. A cytokine that stimulates the activity of B and T cells is

A. lymphotoxin
B. interleukin-2
C. interleukin-1
D. all of these

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18. Which type of cell actually secrets antibodies?

A. plasma cells
B. T cells
C. macrophages
D. dendritic cells

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19. Which of the following is correct?

A. rabbits do not make myelomas whereas mice are unable to synthesize antibodies
B. rabbits do not make myelomas whereas mice are able to synthesize antibodies
C. rabbits make myelomas whereas mice are unable to synthesize antibodies
D. rabbits make myelomas whereas mice are able to synthesize antibodies

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20. The Ig locus is about

A. 2/3^rd of all hybridomas
B. l/3^rd of all hybridomas
C. l/2^nd of all hybridomas
D. 1/4^th of all hybridomas

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